Jagged Ends of Urinary Cell-Free DNA: Characterization and Feasibility Assessment in Bladder Cancer Detection

Zhou, Z; Cheng, SH; Ding, SC; Heung, MMS; Xie, TT; Cheng, THT; Lam, WKJ; Peng, WL; Teoh, JYC; Chiu, PKF; Ng, CF; Jiang, PY; Chan, KCA; Chiu, RWK; Lo, YMD

Lo, YMD (corresponding author), Prince Wales Hosp, Dept Chem Pathol, Shatin, 30-32 Ngan Shing St, Hong Kong, Peoples R China.

CLINICAL CHEMISTRY, 2021; 67 (4): 621

Abstract

BACKGROUND: Double-stranded DNA in plasma is known to carry single-stranded ends, called jagged ends. Plasma DNA jagged ends are biomarkers for pathop......

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