The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism

Cheng, JL; Zhao, Y; Xu, G; Zhang, KR; Jia, WF; Sun, YL; Zhao, J; Xue, J; Hu, YX; Zhang, GZ

Zhang, GZ (reprint author), China Agr Univ, Coll Vet Med, Key Lab Anim Epidemiol, Minist Agr, Beijing 100193, Peoples R China.

VIRUSES-BASEL, 2019; 11 (10):

Abstract

Some coronaviruses (CoVs) have an extra furin cleavage site (RRKR/S, furin-S2' site) upstream of the fusion peptide in the spike protein, which plays ......

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