Targeting CD133 reverses drug-resistance via the AKT/NF-kappa B/MDR1 pathway in colorectal cancer

Yuan, ZT; Liang, X; Zhan, YP; Wang, ZY; Xu, J; Qiu, YY; Wang, J; Cao, YJ; Le, V; Ly, HT; Xu, JH; Li, W; Yin, PH; Xu, K

Yin, PH; Xu, K (corresponding author), Shanghai Univ Tradit Chinese Med, Putuo Hosp, Intervent Canc Inst Chinese Integrat Med, Shanghai 200062, Peoples R China.; Yin, PH; Xu, K (corresponding author), Anhui Med Univ, Shanghai Putuo Cent Sch Clin Med, Hefei 230032, Peoples R China.; Xu, K (corresponding author), Shanghai Univ Tradit Chinese Med, Putuo Hosp, Cent Lab, Shanghai 200062, Peoples R China.; Li, W; Yin, PH (corresponding author), Shanghai Univ Tradit Chinese Med, Putuo Hosp, Dept Gen Surg, Shanghai 200062, Peoples R China.

BRITISH JOURNAL OF CANCER, 2020; 122 (9): 1342

Abstract

Background Recent studies have shown that multidrug resistance may be induced by the high stemness of cancer cells. Following prolonged chemotherapy, ......

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