TGF-beta orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1

Su, J; Morgani, SM; David, CJ; Wang, Q; Er, EE; Huang, YH; Basnet, H; Zou, YL; Shu, WP; Soni, RK; Hendrickson, RC; Hadjantonakis, AK; Massague, J

Massague, J (corresponding author), Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Canc Biol & Genet Program, 1275 York Ave, New York, NY 10021 USA.

NATURE, 2020; 577 (7791): 566

Abstract

Epithelial-to-mesenchymal transitions (EMTs) are phenotypic plasticity processes that confer migratory and invasive properties to epithelial cells dur......

Full Text Link


打开APP