Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

Fu, LN; Hu, YQ; Song, MS; Liu, ZP; Zhang, WQ; Yu, FX; Wu, J; Wang, S; Belmonte, JCI; Chan, P; Qu, J; Tang, FC; Liu, GH

Liu, GH (reprint author), Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Ctr Excellence Biomacromol, Beijing, Peoples R China.; Qu, J (reprint author), Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing, Peoples R China

PLOS BIOLOGY, 2019; 17 (4):

Abstract

Cellular senescence is a driver of various aging-associated disorders, including osteoarthritis. Here, we identified a critical role for Yes-associate......

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