Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis

Jayne, DRW; Bruchfeld, AN; Harper, L; Schaier, M; Venning, MC; Hamilton, P; Burst, V; Grundmann, F; Jadoul, M; Szombati, I; Tesar, V; Segelmark, M; Potarca, A; Schall, TJ; Bekker, P

Jayne, DRW (reprint author), Addenbrookes Hosp, Dept Med, Vasculitis & Lupus Clin, Box 57, Cambridge CB2 2QQ, England.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017; 28 (9): 2756

Abstract

Alternative C activation is involved in the pathogenesis of ANCA-associated vasculitis. However, glucocorticoids used as treatment contribute to the m......

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