Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro

Yi, W; Shi, JJ; Zhao, GG; Zhou, XE; Suino-Powell, K; Melcher, K; Xu, HE

Yi, W (reprint author), Guangzhou Med Univ, Sch Pharmaceut Sci, Guangzhou 511436, Guangdong, Peoples R China.; Yi, W; Xu, HE (reprint author), Chinese Acad Sci, Ctr Struct & Funct Drug Targets, CAS Key Lab Receptor Res, VARI SIMM Ctr,Shanghai Inst Mat Med

Scientific Reports, 2017; 7 ( ):

Abstract

Thiazolidinediones (TZD) function as potent anti-diabetic drugs through their direct action on the nuclear receptor peroxisome proliferator-activated ......

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