Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry

Fontanarosa, C; Pane, F; Sepe, N; Pinto, G; Trifuoggi, M; Squillace, M; Errico, F; Usiello, A; Pucci, P; Amoresano, A

Amoresano, A (reprint author), Univ Naples Federico II, Dept Chem Sci, Naples, Italy.; Amoresano, A (reprint author), Ist Nazl Biostrutture & Biosistemi, Rome, Italy.

PLOS ONE, 2017; 12 (6):

Abstract

Several studies have suggested that free D-Asp has a crucial role in N-methyl D-Asp receptor-mediated neurotransmission playing very important functio......

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