Challenges in benchmarking metagenomic profilers

Sun, Z; Huang, S; Zhang, M; Zhu, QY; Haiminen, N; Carrieri, AP; Vazquez-Baeza, Y; Parida, L; Kim, HC; Knight, R; Liu, YY

Liu, YY (corresponding author), Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.; Liu, YY (corresponding author), Harvard Med Sch, Boston, MA 02115 USA.; Knight, R (corresponding author), Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA.; Knight, R (corresponding author), Univ Calif San Diego, Jacobs Sch Engn, Ctr Microbiome Innovat, La Jolla, CA 92093 USA.; Knight, R (corresponding author), Univ Calif San Diego, Dept Comp Sci & Engn, La Jo

NATURE METHODS, 2021; 18 (6): 618

Abstract

Many computational tools for metagenomic profiling have been developed, with different algorithms and features. This analysis shows that, when compari......

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