Delayed Denosumab Injections and Fracture Risk Among Patients With Osteoporosis A Population-Based Cohort Study

Lyu, HC; Yoshida, K; Zhao, SS; Wei, J; Zeng, C; Tedeschi, SK; Leder, BZ; Lei, GH; Tang, PF; Solomon, DH

Lei, GH (corresponding author), Cent South Univ, Xiangya Hosp, Dept Orthopaed, 87 Xiangya Rd, Changsha 410008, Peoples R China.; Solomon, DH (corresponding author), Brigham & Womens Hosp, Div Rheumatol, 60 Fenwood Rd, Boston, MA 02115 USA.; Tang, PF (corresponding author), Gen Hosp Chinese PLA, Natl Clin Resh Ctr Orthoped Sports Med & Rehabil, 28 Fuxing Rd, Beijing 100853, Peoples R China.

ANNALS OF INTERNAL MEDICINE, 2020; 173 (7): 516

Abstract

Background: Denosumab is effective for osteoporosis, but discontinuation leads to rapid reversal of its therapeutic effect. Objective: To estimate the......

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