Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders-MedSci.cn

Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders

Henning, RJ; Bourgeois, M; Harbison, RD

Henning, RJ (reprint author), James A Haley Vet Hosp, 13000 Bruce B Downs Blvd, Tampa, FL 33612 USA.; Henning, RJ (reprint author), Univ S Florida, Coll Publ Hlth, 13000 Bruce B Downs Blvd, Tampa, FL 33612 USA.

CARDIOVASCULAR TOXICOLOGY, 2018; 18 (6): 493

Abstract

Poly(ADP-ribosyl)ation is an immediate cellular repair response to DNA damage and is catalyzed primarily by poly(ADP-ribose)polymerase-1 (PARP1), whic......

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