Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebp alpha and Cebp delta

Zhang, L; Li, J; Xu, H; Shao, XY; Fu, L; Hou, Y; Hao, CQ; Li, WY; Joshi, K; Wei, W; Xu, Y; Zhang, F; Dai, SJ; Breslin, P; Zhang, JW; Zhang, J

Zhang, JW (corresponding author), Loyola Univ Chicago, Oncol Inst, Cardinal Bernardin Canc Ctr, Maywood, IL 60153 USA.; Zhang, J (corresponding author), Shanghai Normal Univ, Coll Life Sci, Shanghai 200234, Peoples R China.

BLOOD, 2020; 135 (14): 1133

Abstract

c-Myc (Myc hereafter) is found to be deregulated and/or amplified in most acute myeloid leukemias (AMLs). Almost all AML cells are dependent upon Myc ......

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