PTEN Is Fundamental for Elimination of Leukemia Stem Cells Mediated by GSK126 Targeting EZH2 in Chronic Myelogenous Leukemia

Zhou, JF; Nie, DN; Li, J; Du, X; Lu, YH; Li, YQ; Liu, C; Dai, W; Wang, Y; Jin, YL; Pan, JX

Jin, YL; Pan, JX (reprint author), Jinan Univ, Inst Tumor Pharmacol, Coll Pharm, Guangzhou, Guangdong, Peoples R China.; Pan, JX (reprint author), Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, 54 South Xianlie Rd, Guangzhou 510060, G

CLINICAL CANCER RESEARCH, 2018; 24 (1): 145

Abstract

Purpose: Leukemia stem cells (LSCs) are an important source of tyrosine kinase inhibitor resistance and disease relapse in patients with chronic myelo......

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