MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling

Tan, CT; Chang, HC; Zhou, QL; Yu, CD; Fu, NY; Sabapathy, K; Yu, VC

Yu, VC (corresponding author), Natl Univ Singapore, Dept Pharm, Singapore, Singapore.

EMBO REPORTS, ; ():

Abstract

Nrf2 signaling is vital for protecting cells against oxidative stress. However, its hyperactivation is frequently found in liver cancer through excess......

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