ACY-1215 exhibits anti-inflammatory and chondroprotective effects in human osteoarthritis chondrocytes via inhibition of STAT3 and NF-kappa B signaling pathways

Cheng, C; Shan, WS; Huang, W; Ding, ZF; Cui, GJ; Liu, F; Lu, W; Xu, JG; He, W; Yin, ZS

Yin, ZS (reprint author), Anhui Med Univ, Affiliated Hosp 4, Dept Orthopaed, 372 Tun Xi Rd, Hefei 230032, Anhui, Peoples R China.; He, W (reprint author), Anhui Med Univ, Sch Basic Med Sci, 81 Mei Shan Rd, Hefei 230032, Anhui, Peoples R China.

BIOMEDICINE & PHARMACOTHERAPY, 2019; 109 (): 2464

Abstract

Cartilage degeneration is a basic pathological feature of osteoarthritis (OA), and there is growing evidence that it is associated with inflammation. ......

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