CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system

Lee, J; Lim, H; Jang, H; Hwang, B; Lee, JH; Cho, J; Lee, JH; Bang, D

Bang, D (reprint author), Yonsei Univ, Dept Chem, Seoul 03722, South Korea.; Lee, JH (reprint author), Kyung Hee Univ, Dept Clin Pharmacol & Therapeut, Coll Med, Seoul 02447, South Korea.; Lee, JH (reprint author), Kyung Hee Univ, Kyung Hee Med Sci Res In

NUCLEIC ACIDS RESEARCH, 2019; 47 (1):

Abstract

Existing methods to enrich target regions of genomic DNA based on PCR, hybridization capture, or molecular inversion probes have various drawbacks, in......

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