Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-kappa B pathway and the NLRP3 inflammasome may be involved in the mechanism

Yin, DP; Zhou, S; Xu, X; Gao, WW; Li, F; Ma, YY; Sun, DD; Wu, YG; Guo, Q; Liu, HM; Han, LL; Wang, ZG; Wang, Y; Zhang, JN

Wang, Y; Zhang, JN (reprint author), Tianjin Med Univ, Gen Hosp, Dept Neurosurg, 154 Anshan Rd, Tianjin 300052, Peoples R China.

BRAIN RESEARCH, 2018; 1698 (): 1

Abstract

Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly select......

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