Rational Selection of CRISPR-Cas Triggering Homology-Directed Repair in Human Cells

Li, FF; Zhou, CC; Tu, TX; Liu, YY; Lv, XJ; Wang, B; Song, ZM; Zhao, QF; Liu, CB; Gu, F; Zhao, JZ

Zhao, JZ (corresponding author), Wenzhou Med Univ, Affiliated Hosp 2, 109 Xueyuan West Rd, Wenzhou 325027, Zhejiang, Peoples R China.; Zhao, JZ (corresponding author), Wenzhou Med Univ, Yuying Childrens Hosp, 109 Xueyuan West Rd, Wenzhou 325027, Zhejiang, Peoples R China.; Gu, F (corresponding author), Wenzhou Med Univ, Eye Hosp, 270 Xueyuan West Rd, Wenzhou 325027, Zhejiang, Peoples R China.

HUMAN GENE THERAPY, 2021; 32 (5-6): 302

Abstract

The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas (CRISPR-associated) nucleases have been widely applied for genome engineerin......

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