Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer

Clarke, PA; Roe, T; Swabey, K; Hobbs, SM; McAndrew, C; Tomlin, K; Westwood, I; Burke, R; van Montfort, R; Workman, P

Clarke, PA (reprint author), Inst Canc Res, Canc Res UK Canc Therapeut Unit, London SM2 5NG, England.

ONCOGENE, 2019; 38 (25): 5076

Abstract

Genomic alterations in cancer cells result in vulnerabilities that clinicians can exploit using molecularly targeted drugs, guided by knowledge of the......

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