Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates

Goedeke, L; Peng, L; Montalvo-Romeral, V; Butrico, GM; Dufour, S; Zhang, XM; Perry, RJ; Cline, GW; Kievit, P; Chng, K; Petersen, KF; Shulman, GI

Shulman, GI (reprint author), Yale Sch Med, Dept Internal Med, New Haven, CT 06510 USA.; Shulman, GI (reprint author), Yale Sch Med, Dept Cellular & Mol Physiol, New Haven, CT 06510 USA.

SCIENCE TRANSLATIONAL MEDICINE, 2019; 11 (512):

Abstract

Nonalcoholic fatty liver disease (NAFLD) is estimated to affect up to one-third of the general population, and new therapies are urgently required. Ou......

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