Smoothened Promotes Glioblastoma Radiation Resistance Via Activating USP3-Mediated Claspin Deubiquitination

Tu, YM; Chen, ZY; Zhao, PZ; Sun, GC; Bao, ZY; Chao, HL; Fan, L; Li, C; You, YP; Qu, Y; Chen, Y; Ji, J

Ji, J (corresponding author), Nanjing Med Univ, Affiliated Hosp 1, Dept Neurosurg, Nanjing 210029, Jiangsu, Peoples R China.; Qu, Y (corresponding author), Air Force Med Univ, Tangdu Hosp, Dept Neurosurg, Xian, Peoples R China.; Chen, Y (corresponding author), Nanjing Med Univ, Dept Immunol, Nanjing 211166, Peoples R China.

CLINICAL CANCER RESEARCH, 2020; 26 (7): 1749

Abstract

Purpose: Glioblastoma (GBM) is one of the most aggressive and lethal cancer types in humans. The standard treatment approach is surgery followed by ch......

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