Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing

Li, JY; Zhou, X; Liu, XM; Ren, J; Wang, JL; Wang, WD; Zheng, YX; Shi, XY; Sun, T; Li, ZF; Kang, AD; Tang, FC; Wen, L; Fu, W

Wen, L (reprint author), Peking Univ, Biomed Pioneering Innovat Ctr BIOPIC, 5 Yiheyuan Rd, Beijing 100871, Peoples R China.; Fu, W (reprint author), Peking Univ, Dept Gen Surg, Hosp 3, 49 North Garden Rd, Beijing 100191, Peoples R China.

CLINICAL CHEMISTRY, 2019; 65 (7): 916

Abstract

BACKGROUND: Aberrant DNA hypermethylation of CpG islands occurs frequently throughout the genome in human colorectal cancer (CRC). A genome-wide DNA h......

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