AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease

Nikolaou, N; Gathercole, LL; Marchand, L; Althari, S; Dempster, NJ; Green, CJ; van de Bunt, M; McNeil, C; Arvaniti, A; Hughes, BA; Sgromo, B; Gillies, RS; Marschall, HU; Penning, TM; Ryan, J; Arlt, W; Hodson, L; Tomlinson, JW

Tomlinson, JW (reprint author), Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford OX3 7LJ, England.

METABOLISM-CLINICAL AND EXPERIMENTAL, 2019; 99 (): 67

Abstract

Objective: Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome. Steroid hormones and bile acids are potent re......

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