Therapeutic PD-L1 antibodies are more effective than PD-1 antibodies in blocking PD-1/PD-L1 signaling

Linhares, AD; Battin, C; Jutz, S; Leitner, J; Hafner, C; Tobias, J; Wiedermann, U; Kundi, M; Zlabinger, GJ; Grabmeier-Pfistershammer, K; Steinberger, P

Steinberger, P (reprint author), Med Univ Vienna, Ctr Pathophysiol, Div Immune Receptors & T Cell Activat, Infectiol, Vienna, Austria.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

Inhibitors of PD-1 signaling have revolutionized cancer therapy. PD-1 and PD-L1 antibodies have been approved for the treatment of cancer. To date, th......

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