Combining radiation to EGFR and Bcl-2 blockade: a new approach to target cancer stem cells in head and neck squamous cell carcinoma

Guy, JB; Espenel, S; Louati, S; Gauthier, A; Garcia, MA; Vial, N; Malesys, C; Ardail, D; Alphonse, G; Wozny, AS; Rodriguez-Lafrasse, C; Magne, N

Guy, JB (corresponding author), Univ Lyon 1, Fac Med Lyon Sud, F-69921 Oullins, France.; Guy, JB (corresponding author), CNRS UMR 5822 IP2I, Fac Med Lyon Sud, Lab Radiobiol Cellulaire & Mol, 165 Chemin Grand Revoyet,BP 12, F-69921 Oullins, France.; Guy, JB (corresponding author), Inst Cancerol Loire, Dept Radiotherapie, F-42270 St Priest En Jarez, France.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (7): 1905

Abstract

Purpose The clinical outcome of head and neck squamous cell carcinoma (HNSCC) remains poor, partly due to the presence of resistant cancer stem cells ......

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