In-Cell Chemical Crosslinking Identifies Hotspots for SQSTM-1/p62-IKBα Interaction That Underscore a Critical Role of p62 in Limiting NF-KB Activation Through IKBα Stabilization

Liu, Y; Trnka, MJ; He, L; Burlingame, AL; Correia, MA

Correia, MA (通讯作者)，Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94122 USA.;Correia, MA (通讯作者)，Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94122 USA.;Correia, MA (通讯作者)，Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94122 USA.;Correia, MA (通讯作者)，Univ Calif San Francisco, Liver Ctr, San Francisco, CA 94122 USA.

MOLECULAR & CELLULAR PROTEOMICS, 2023; 22 (2):

Abstract

We have previously documented that in liver cells, multifunctional protein scaffold p62/SQSTM1 is closely associated with IxBa, an inhibitor of the tr......

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