MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation

Zhu, BL; Long, Y; Luo, W; Yan, Z; Lai, YJ; Zhao, LG; Zhou, WH; Wang, YJ; Shen, LL; Liu, L; Deng, XJ; Wang, XF; Sun, F; Chen, GJ

Chen, GJ (reprint author), Chongqing Med Univ, Chongqing Key Lab Neurol, Affiliated Hosp 1, Dept Neurol, 1 Youyi Rd, Chongqing 400016, Peoples R China.

BRAIN, 2019; 142 (): 176

Abstract

BACE1 is the rate-limiting enzyme in amyloid- generation. Zhu et al. report that selective inhibition of matrix metallopeptidase 13 (MMP13) decreases ......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索