Hypermutated tumours across 11 cancer types show three distinct immune subtypes

Hu, WX; Chen, JN; Qi, LN; Ge, WT; Zheng, S; Yang, YM

Hu, WX (corresponding author), Zhejiang Univ, Sch Med, Canc Inst,Affiliated Hosp 2, Key Lab Canc Prevent & Intervent,China Natl Minis, Hangzhou 310009, Zhejiang, Peoples R China.; Yang, YM (corresponding author), Zhejiang Univ, Womens Hosp, Key Lab Reprod & Genet, Minist Educ,Sch Med, Hangzhou 310006, Zhejiang, Peoples R China.

EUROPEAN JOURNAL OF CANCER, 2021; 148 (): 230

Abstract

Background: Complete remission is observed in less than half of hypermutated (HM) tumours after immune checkpoint blockade therapy, indicating that HM......

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