EGFR/Notch Antagonists Enhance the Response to Inhibitors of the PI3K-Akt Pathway by Decreasing Tumor-Initiating Cell Frequency

Fu, WY; Lei, CH; Yu, Y; Liu, SW; Li, T; Lin, FX; Fan, XY; Shen, YF; Ding, M; Tang, Y; Ye, XT; Yang, YJ; Hu, S

Hu, S (reprint author), Second Mil Med Univ, 800 Xiangyin Rd, Shanghai 200433, Peoples R China.

CLINICAL CANCER RESEARCH, 2019; 25 (9): 2835

Abstract

Purpose: Both EGFR and PI3K-Akt signaling pathways have been used as therapeutically actionable targets, but resistance is frequently reported. In thi......

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