Human RAP1 specifically protects telomeres of senescent cells from DNA damage

Lototska, L; Yue, JX; Li, J; Giraud-Panis, MJ; Zhou, SY; Royle, NJ; Liti, G; Ye, J; Gilson, E; Mendez-Bermudez, A

Ye, J; Gilson, E; Mendez-Bermudez, A (corresponding author), Shanghai Jiao Tong Univ, Int Res Lab Hematol Canc & Aging,Sch Med, Shanghai Ruijin Hosp,Shanghai Ruijin Hosp North, State Key Lab Med Genom,Univ Cote Azur,CNRS,INSER, Shanghai, Peoples R China.; Gilson, E; Mendez-Bermudez, A (corresponding author), Univ Cote Azur, CNRS, INSERM, IRCAN,Med Sch Nice, Nice, France.; Gilson, E (corresponding author), CHU Nice, Dept Genet, Nice, France.

EMBO REPORTS, 2020; 21 (4):

Abstract

Repressor/activator protein 1 (RAP1) is a highly evolutionarily conserved protein found at telomeres. Although yeast Rap1 is a key telomere capping pr......

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