The 11 beta-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C-19 steroids with 11 beta HSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis

Gent, R; du Toit, T; Bloem, LM; Swart, AC

Swart, AC (reprint author), Stellenbosch Univ, Dept Biochem, Private Bag X1, ZA-7602 Matieland, South Africa.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2019; 189 (): 116

Abstract

The 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) types 1 and 2 are primarily associated with glucocorticoid inactivation and reactivation. Sever......

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