HLA-E-restricted, Gag-specific CD8(+) T cells can suppress HIV-1 infection, offering vaccine opportunities

Yang, HB; Rei, M; Brackenridge, S; Brenna, E; Sun, H; Abdulhaqq, S; Liu, MKP; Ma, WW; Kurupati, P; Xu, XN; Cerundolo, V; Jenkins, E; Davis, SJ; Sacha, JB; Fruh, K; Picker, LJ; Borrow, P; Gillespie, GM; McMichael, AJ

McMichael, AJ (corresponding author), Univ Oxford, Nuffield Dept Med, NDM Res Bldg, Oxford OX3 7FZ, England.

SCIENCE IMMUNOLOGY, 2021; 6 (57):

Abstract

Human leukocyte antigen-E (HLA-E) normally presents an HLA class Ia signal peptide to the NKG2A/C-CD94 regulatory receptors on natural killer (NK) cel......

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