Directing differentiation of human induced pluripotent stem cells toward androgen-producing Leydig cells rather than adrenal cells

Li, L; Li, YC; Sottas, C; Culty, M; Fan, JJ; Hu, YM; Cheung, G; Chemes, HE; Papadopoulos, V

Papadopoulos, V (reprint author), Univ Southern Calif, Sch Pharm, Dept Pharmacol & Pharmaceut Sci, Los Angeles, CA 90089 USA.; Papadopoulos, V (reprint author), McGill Univ Hlth Ctr, Res Inst, Montreal, PQ H4A 3J1, Canada.; Papadopoulos, V (reprint author

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (46): 23274

Abstract

Reduced serum testosterone (T), or hypogonadism, affects millions of men and is associated with many pathologies, including infertility, cardiovascula......

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