WT1 protein is cleaved by caspase-3 in apoptotic leukemic cells

Ruan, JC; Gao, SM; Yang, JJ; Li, HY; Huang, H; Zheng, XQ

Zheng, XQ (reprint author), Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325027, Zhejiang, Peoples R China.; Zheng, XQ (reprint author), Wenzhou Med Univ, Dept Lab Med, Affiliated Hosp 2, Wenzhou 325027, Zhejiang, Peoples R China.

LEUKEMIA & LYMPHOMA, 2018; 59 (1): 162

Abstract

The aberrant overexpression of Wilms' tumor-1 gene (WT1) plays an important role in blast cell survival and resistance to chemotherapy in acute myeloi......

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