Noninvasive Detection of Bladder Cancer by Shallow-Depth Genome-Wide Bisulfite Sequencing of Urinary Cell-Free DNA for Methylation and Copy Number Profiling

Cheng, THT; Jiang, PY; Teoh, JYC; Heung, MMS; Tam, JCW; Sun, X; Lee, WS; Ni, M; Chan, RCK; Ng, CF; Chan, KCA; Chiu, RWK; Lo, YMD

Lo, YMD (reprint author), Prince Wales Hosp, Dept Chem Pathol, Shatin, Hong Kong, Peoples R China.

CLINICAL CHEMISTRY, 2019; 65 (7): 927

Abstract

BACKGROUND: The current diagnosis and monitoring of bladder cancer are heavily reliant on cystoscopy, an invasive and costly procedure. Previous effor......

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