Unaccompanied mechanosensory domain mediates low expression of glycoprotein Ib alpha: implications for Bernard-Soulier syndrome

Tao, Y; Gan, C; Zhang, XQ; Liu, LB; Zakas, PM; Doering, CB; Mo, X; Li, RH

Mo, X (reprint author), Shanghai Childrens Med Ctr, 1678 Dongfang Rd, Shanghai 200127, Peoples R China.; Li, RH (reprint author), Emory Univ, Dept Pediat, 2015 Uppergate Dr NE,Room 440, Atlanta, GA 30322 USA.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020; 18 (2): 510

Abstract

Background Disruption of protein folding or inter-subunit interactions in the platelet glycoprotein (GP)Ib-IX complex leads to its abnormally low expr......

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