Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery

Long, L; Xiong, W; Lin, FW; Hou, JZ; Chen, GH; Peng, TX; He, YH; Wang, R; Xu, Q; Huang, YZ

Xu, Q; Huang, YZ (通讯作者)，Guangzhou Univ Chinese Med, Artemisinin Res Ctr, Guangzhou 510450, Peoples R China.;Huang, YZ (通讯作者)，Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China.;Huang, YZ (通讯作者)，Chinese Acad Sci, Zhongshan Inst Drug Discovery, Shanghai Inst Mat Med, Zhongshan 528437, Peoples R China.;Huang, YZ (通讯作者)，NMPA Key Lab Qual Res & Evaluat Pharmaceut Excipie, Shanghai 201203, Peoples R China.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2023; 42 (1):

Abstract

Background There are few effective medications for treating colorectal cancer and liver metastases (CRLM). The interactions among glycolysis, epitheli......

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