T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1

Zhu, HC; Zhang, LZ; Wu, YL; Dong, BJ; Guo, WL; Wang, M; Yang, L; Fan, XY; Tang, YL; Liu, NS; Lei, XG; Wu, H

Wu, H (reprint author), Peking Univ, Sch Life Sci, MOE Key Lab Cell Proliferat & Differentiat, Beijing, Peoples R China.; Wu, H (reprint author), Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China.; Wu, H (reprint author), Peking Univ, Be

ELIFE, 2018; 7 ():

Abstract

Leukemia stem cells (LSCs) are regarded as the origins and key therapeutic targets of leukemia, but limited knowledge is available on the key determin......

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