Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer's disease and mild cognitive impairment

Lu, R; Wang, J; Tao, R; Wang, J; Zhu, T; Guo, W; Sun, Y; Li, H; Gao, Y; Zhang, W; Fowler, CJ; Li, Q; Chen, S; Wu, Z; Masters, CL; Zhong, C; Jing, N; Wang, Y; Wang, Y

Wang, Y (reprint author), Chinese Acad Sci, Inst Neurosci, Lab Neural Signal Transduct, 320 Yue Yang Rd, Shanghai 200031, Peoples R China.

MOLECULAR PSYCHIATRY, 2018; 23 (3): 767

Abstract

Transient receptor potential canonical 6 (TRPC6) inhibits beta-amyloid (A beta) production. Hyperforin, the TRPC6 agonist, reduces A beta levels and i......

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