Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation

Li, YY; Jin, C; Bai, H; Gao, YX; Sun, S; Chen, L; Qin, L; Liu, PP; Cheng, LZ; Wang, QF

Wang, QF (reprint author), Chinese Acad Sci, Beijing Inst Genom, 1 Beichen West Rd, Beijing 100101, Peoples R China.; Cheng, LZ (reprint author), Johns Hopkins Univ, Sch Med, Inst Cell Engn, Edward Miller Res Bldg 747,733 North Broadway, Baltimore, MD 212

BLOOD, 2018; 131 (2): 191

Abstract

Megakaryocytes (MKs) in adult marrow produce platelets that play important roles in blood coagulation and hemostasis. Monoallelic mutations of the mas......

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