HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis

Liu, TY; Xiang, A; Peng, T; Doran, AC; Tracey, KJ; Barnes, BJ; Tabas, I; Son, M; Diamond, B

Son, M; Diamond, B (reprint author), Feinstein Inst Med Res, Ctr Autoimmune Musculoskeletal & Hematopoiet Dis, Manhasset, NY 11030 USA.; Son, M; Diamond, B (reprint author), Donald & Barbara Zucker Sch Med Hofstra Northwell, MD PhD Program, Hempstead, NY

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (46): 23254

Abstract

Macrophage polarization is critical to inflammation and resolution of inflammation. We previously showed that high-mobility group box 1 (HMGB1) can en......

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