Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration

Yang, C; Wang, X; Wang, JY; Wang, XJ; Chen, WT; Lu, N; Siniossoglou, S; Yao, ZP; Liu, K

Liu, K (corresponding author), Hong Kong Univ Sci & Technol, Div Life Sci, State Key Lab Mol Neurosci, Hong Kong, Peoples R China.; Liu, K (corresponding author), Shenzhen Peking Univ Hong Kong Univ Sci & Technol, Biomed Res Inst, Shenzhen Key Lab Neuronal Struct Biol, Shenzhen, Peoples R China.; Liu, K (corresponding author), Hong Kong Univ Sci & Technol, Sch Sci, Ctr Syst Biol & Human Hlth, Hong Kong, Peoples R China.; Liu, K (corresponding author), Hong Kong Univ Sci & Technol, Inst Adv Study, Hong Kong, Peoples R China.

NEURON, 2020; 105 (2): 276

Abstract

How adult neurons coordinate lipid metabolism to regenerate axons remains elusive. We found that depleting neuronal lipin1, a key enzyme controlling t......

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