Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis

Liu, QM; Yu, JJ; Wang, LH; Tang, YL; Zhou, Q; Ji, SH; Wang, Y; Santos, L; Haeusler, RA; Que, JW; Rajbhandari, P; Lei, XG; Valenti, L; Pajvani, UB; Qin, J; Qiang, L

Qiang, L (corresponding author), Columbia Univ, Med Ctr, Russ Berrie Bldg Room 607A,1150 St Nicholas Ave, New York, NY 10032 USA.; Pajvani, UB (corresponding author), Columbia Univ, Med Ctr, Russ Berrie Bldg Room 121F,1150 St Nicholas Ave, New York, NY 10032 USA.; Qin, J (corresponding author), Verna & Marrs McLean Dept Biochem & Mol Biol, One Baylor Plaza,Room 145E, Houston, TX 77030 USA.

JOURNAL OF HEPATOLOGY, 2020; 73 (2): 361

Abstract

Background & Aims: Obesity is a well-established risk factor for type 2 diabetes (T2D) and non-alcoholic steatohepatitis (NASH), but the underlyin......

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