Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE

Msallam, R; Balla, J; Rathore, APS; Kared, H; Malleret, B; Saron, WAA; Liu, ZY; Hang, JW; Dutertre, CA; Larbi, A; Chan, JKY; St John, AL; Ginhoux, F

Ginhoux, F (corresponding author), ASTAR, Singapore Immunol Network SIgN, Singapore 138648, Singapore.; St John, AL (corresponding author), Duke NUS Med Sch, Program Emerging Infect Dis, Singapore 169857, Singapore.; St John, AL (corresponding author), Duke Univ, Dept Pathol, Med Ctr, Durham, NC 27705 USA.; St John, AL (corresponding author), Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Microbiol & Immunol, Singapore 117545, Singapore.; Ginhoux, F (corresponding author), Shanghai Jiao Tong Univ, Shanghai Inst Immunol, Sch Med, Shanghai 200025, Peoples R China.; St John, AL (corresponding author), SingHlth Duke NUS Global Hlth Inst, Singapore 169857, Singapore.; Ginhoux, F (corresponding author), Translat Immunol Inst, SingHlth Duke NUS Acad Med Ctr, Acad, Singapore 169856, Singapore.

SCIENCE, 2020; 370 (6519): 941

Abstract

Mast cells (MCs) are central effector cells in allergic reactions that are often mediated by immunoglobulin E (IgE). Allergies commonly start at an ea......

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