Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

Szmyd, R; Niska-Blakie, J; Diril, MK; Nunes, PR; Tzelepis, K; Lacroix, A; van Hul, N; Deng, LW; Matos, J; Dreesen, O; Bisteau, X; Kaldis, P

Kaldis, P (reprint author), ASTAR, IMCB, 61 Biopolis Dr,Proteos 3-09, Singapore 138673, Singapore.; Kaldis, P (reprint author), NUS, Dept Biochem, Singapore 117597, Singapore.

ONCOGENE, 2019; 38 (7): 998

Abstract

Cell cycle regulation, especially faithful DNA replication and mitosis, are crucial to maintain genome stability. Cyclin-dependent kinase (CDK)/cyclin......

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