The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity

Lu, D; Liu, L; Sun, YZ; Song, J; Yin, Q; Zhang, GZ; Qi, F; Hu, ZX; Yang, ZL; Zhou, Z; Hu, Y; Zhang, LH; Ji, JF; Zhao, XY; Jin, Y; McNutt, MA; Yin, YX

Yin, YX (corresponding author), Peking Univ, Hlth Sci Ctr, Inst Syst Biomed, Beijing, Peoples R China.; Yin, YX (corresponding author), Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Pathol, Beijing, Peoples R China.; Yin, YX (corresponding author), Peking Univ, Hlth Sci Ctr, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China.; Yin, YX (corresponding author), Peking Univ, Hlth Sci Ctr, Beijing Key Lab Tumor Syst Biol, Beijing, Peoples R China.

NATURE IMMUNOLOGY, 2020; 21 (3): 287

Abstract

Cancer cells subvert immune surveillance through inhibition of T cell effector function. Elucidation of the mechanism of T cell dysfunction is therefo......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索