PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36

Qi, ZY; Hu, L; Zhang, JJ; Yang, WL; Liu, X; Jia, DL; Yao, ZF; Chang, L; Pan, GX; Zhong, HX; Luo, XP; Yao, K; Sun, AJ; Qian, JY; Ding, ZR; Ge, JB

Ge, JB (corresponding author), Fudan Univ, Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Dept Cardiol, 180 Fenglin Rd, Shanghai 200032, Peoples R China.; Ding, ZR (corresponding author), Fudan Univ, Sch Basic Med Sci, Dept Biochem & Mol Biol, 130 Dongan Rd, Shanghai 200032, Peoples R China.

CIRCULATION, 2021; 143 (1): 45

Abstract

Background: PCSK9 (proprotein convertase subtilisin/kexin 9), mainly secreted by the liver and released into the blood, elevates plasma low-density li......

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