Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis

Rao, W; Wang, S; Duleba, M; Niroula, S; Goller, K; Xie, JZ; Mahalingam, R; Neupane, R; Liew, AA; Vincent, M; Okuda, K; O'Neal, WK; Boucher, RC; Dickey, BF; Wechsler, ME; Ibrahim, O; Engelhardt, JF; Mertens, TCJ; Wang, W; Jyothula, SSK; Crum, CP; Karmouty-Quintana, H; Parekh, KR; Metersky, ML; McKeon, FD; Xian, W

McKeon, FD; Xian, W (corresponding author), Univ Houston, Stem Cell Ctr, Dept Biol & Biochem, Houston, TX 77003 USA.; McKeon, FD; Xian, W (corresponding author), Univ Houston, Stem Cell Ctr, Dept Biol & Biochem, Houston, TX 77004 USA.

CELL, 2020; 181 (4): 848

Abstract

Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic bronchitis, small airway obstruction, and emphysema that represents......

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