TRUST4: immune repertoire reconstruction from bulk and single-cell RNA-seq data

Song, L; Cohen, D; Ouyang, ZY; Cao, Y; Hu, XH; Liu, XS

Liu, XS (corresponding author), Dana Farber Canc Inst, Dept Data Sci, Boston, MA 02115 USA.; Liu, XS (corresponding author), Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA.; Liu, XS (corresponding author), Dana Farber Canc Inst, Ctr Funct Canc Epigenet, Boston, MA 02115 USA.

NATURE METHODS, 2021; 18 (6): 627

Abstract

We introduce the TRUST4 open-source algorithm for reconstruction of immune receptor repertoires in alpha beta/gamma delta T cells and B cells from RNA......

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