TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons

Nagano, S; Jinno, J; Abdelhamid, RF; Jin, YS; Shibata, M; Watanabe, S; Hirokawa, S; Nishizawa, M; Sakimura, K; Onodera, O; Okada, H; Okada, T; Saito, Y; Takahashi-Fujigasaki, J; Murayama, S; Wakatsuki, S; Mochizuki, H; Araki, T

Nagano, S; Araki, T (corresponding author), Natl Ctr Neurol & Psychiat, Natl Inst Neurosci, Dept Peripheral Nervous Syst Res, Tokyo, Japan.; Nagano, S (corresponding author), Osaka Univ, Dept Neurol, Grad Sch Med, Osaka, Japan.

ACTA NEUROPATHOLOGICA, 2020; 140 (5): 695

Abstract

Mislocalization and abnormal deposition of TDP-43 into the cytoplasm (TDP-43 proteinopathy) is a hallmark in neurons of amyotrophic lateral sclerosis ......

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